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Plasmapheresis in Acute Episodes of Fulminant CNS Inflammatory Demyelination Neurol 43:1100-1104, Rodriquez,M.,et al, 1993 See this aricle in Pubmed Article Abstract We present six patients with acute fulminant episodes of CNS inflammatory demyelination who responded to therapeutic plasmapheresis after failing a course of high-dose methylprednisolone administered IV.Neurologic improvement occurred in three of the patients following the second plasmapheresis.Dramatic improvement in motor function(four patients)and language(two patients)began within 2 to 14 days and persisted during the 6 to 35 months(mean,15 months)of follow-up.Results of this uncontrolled study suggest that plasmapheresis in the absence of other immunosuppressive drugs may have a role in the treatment of severe episodes of inflammatory demyelination in a select subset of MS patients.

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(click to filter results - removes previous filter) multiple sclerosis multiple sclerosis,acute multiple sclerosis,treatment of plasmapheresis treatment of neurologic disorder

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